| Jogo | Data | Hora | EqCasa | GlC | GlF | EqFora |
|---|---|---|---|---|---|---|
| 3 | 2021-10-29 | 20:15 | Arouca | 2 | 0 | Tondela |
| 6 | 2021-10-30 | 17:00 | FC Porto | 4 | 1 | Boavista |
| 2 | 2021-10-30 | 19:00 | Estoril Praia | 1 | 1 | Benfica |
| 9 | 2021-10-30 | 21:15 | Sporting | 1 | 0 | V. Guimarães |
| 1 | 2021-10-31 | 15:30 | Marítimo | 1 | 2 | Gil Vicente |
| 4 | 2021-10-31 | 18:00 | Belenenses SAD | 2 | 1 | Santa Clara |
| 5 | 2021-10-31 | 20:30 | FC Famalicão | 1 | 1 | FC Vizela |
| 7 | 2021-11-01 | 19:00 | SC Braga | 3 | 0 | Portimonense |
| 8 | 2021-11-01 | 21:15 | Moreirense | 1 | 1 | P. Ferreira |