| Jogo | Data | Hora | EqCasa | GlC | GlF | EqFora |
|---|---|---|---|---|---|---|
| 6 | 2022-02-25 | 20:15 | Belenenses SAD | 0 | 2 | P. Ferreira |
| 1 | 2022-02-26 | 15:15 | FC Famalicão | 2 | 1 | Tondela |
| 9 | 2022-02-26 | 18:00 | Marítimo | 1 | 1 | Sporting |
| 5 | 2022-02-26 | 20:30 | Arouca | 1 | 1 | Moreirense |
| 3 | 2022-02-27 | 15:30 | FC Vizela | 1 | 1 | Portimonense |
| 2 | 2022-02-27 | 18:00 | Estoril Praia | 2 | 3 | Boavista |
| 8 | 2022-02-27 | 18:00 | Benfica | 3 | 0 | V. Guimarães |
| 4 | 2022-02-27 | 20:30 | FC Porto | 1 | 1 | Gil Vicente |
| 7 | 2022-02-28 | 20:15 | SC Braga | 0 | 0 | Santa Clara |