| Jogo | Data | Hora | EqCasa | GlC | GlF | EqFora |
|---|---|---|---|---|---|---|
| 4 | 2021-08-27 | 19:00 | Belenenses SAD | 1 | 1 | Moreirense |
| 2 | 2021-08-27 | 21:15 | Estoril Praia | 2 | 1 | Marítimo |
| 3 | 2021-08-28 | 15:30 | FC Vizela | 1 | 1 | Boavista |
| 9 | 2021-08-28 | 18:00 | FC Porto | 3 | 0 | Arouca |
| 5 | 2021-08-28 | 20:30 | FC Famalicão | 1 | 1 | Sporting |
| 6 | 2021-08-29 | 18:00 | Benfica | 2 | 1 | Tondela |
| 7 | 2021-08-29 | 18:00 | SC Braga | 0 | 0 | V. Guimarães |
| 1 | 2021-08-29 | 20:30 | Portimonense | 0 | 1 | P. Ferreira |
| 8 | 2021-08-29 | 20:30 | Santa Clara | 1 | 0 | Gil Vicente |