| Jogo | Data | Hora | EqCasa | GlC | GlF | EqFora |
|---|---|---|---|---|---|---|
| 9 | 2021-09-24 | 19:00 | Sporting | 1 | 0 | Marítimo |
| 4 | 2021-09-24 | 21:15 | Gil Vicente | 1 | 2 | FC Porto |
| 5 | 2021-09-25 | 15:30 | Moreirense | 2 | 1 | Arouca |
| 8 | 2021-09-25 | 18:00 | V. Guimarães | 1 | 3 | Benfica |
| 1 | 2021-09-25 | 20:30 | Tondela | 3 | 2 | FC Famalicão |
| 7 | 2021-09-26 | 18:00 | Santa Clara | 1 | 1 | SC Braga |
| 3 | 2021-09-26 | 20:30 | Portimonense | 0 | 0 | FC Vizela |
| 6 | 2021-09-27 | 19:00 | P. Ferreira | 2 | 2 | Belenenses SAD |
| 2 | 2021-09-27 | 21:15 | Boavista | 1 | 1 | Estoril Praia |